Page 10 - Clinical Connections - Spring 2024
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RVC RESEARCH    STUDY    VETERINARY SERVICES       RVC.AC.UK
         Equine

        HEADSHAKING – TREATMENT OVERVIEW

        Melanie Perrier, Senior Lecturer in Equine Soft Tissue Surgery

               ccasional  shaking  of  the  head   Transverse image at the level of the mandibular   used. Cyproheptadine, a centrally acting
               may be normal, however when   08s  cheek  teeth.  There  is  a  complete   antihistamine and serotonin antagonist, is
        O becoming frequent, violent and     longitudinal fracture along 308 (arrowheads),   used, but research findings on efficacy are
                                             dividing it into two big fragments and exposing
        when affecting riding or handling the horse,   the pulp canals that show a heterogeneous   mixed.
        a pathological process must be considered.   appearance with gas         Magnesium may have neuroprotective
        Conditions  which  can  cause  headshaking                              effects  on  nerve  firing  that  potentially
        include  otitis  interna,  cranial  nerve                               dampen signs of neuropathic pain. In one
        dysfunction, cervical injury, ocular disease,                           study, intravenous infusion of magnesium
        guttural  pouch  mycosis,  dental  disease,                             sulphate was used in six horses with
        sinusitis and behavioural or rider issues.                              headshaking signs. Horses were evaluated
          In  98%  of  cases,  when  no  physical                               up to two hours after IV Mg infusion and an
        cause could be determined, headshaking                                  increased in magnesium blood levels was
        is  classified  as  idiopathic  headshaking.                            noted. This resulted in a 29% reduction in
        Idiopathic  headshaking  is  a  complex                                 headshaking.
        pathology, which can be frustrating for both                             Sodium cromoglycate eyedrops have
        owner and veterinarian.                                                 also been used for their mast cell stabilising
          Trigeminal mediated headshaking or                                    properties.  Three  seasonally  affected
        idiopathic  headshaking  is  defined  as                                horses were treated and all returned to
        an  acquired  disorder  of  the  horse.  The                            ridden exercise.
        headshaking is typically worst at exercise                               Percutaneous    Electrical  Nerve
        with only some horses being affected also at                            Stimulation (PENS) is a treatment translated
        rest. Seasonality of clinical signs has been                            from electrical nerve neuromodulation.
        reported in about 60% of cases, the majority                            As such it may normalise neural function.
        being in spring and summer.                                             Complication rates were reported in up
                                              CT is a useful tool to rule out primary   to  8.8%  of  cases  and  are  usually  mild
        Diagnosis                           disease for which treatment could result   and transient. Remission of headshaking
        The diagnosis is usually one of exclusion   in improvement of headshaking.  An RVC   following the initial course occurred in 53%.
        and should include a complete physical   study found that, in more than 20% of the   Median length of time recorded in remission
        examination  and  a  ridden  examination.   cases, a treatable primary condition was   was 9.5 weeks.
        Further diagnostics may include dental   identified – leading to complete resolution of   PENS  is  believed  to  be  a  good  first-
        examination,  dental endoscopy,  otoscopy,   clinical signs.            line treatment for horses which do not
        maxillary nerve block (if the clinical signs   Clinically  relevant primary diseases   respond  to  a  nose  net.  More  recently,
        are reproducible and consistent), upper   in  that study  included  dental  fracture,   electroacupuncture has been used to
        airways endoscopy, skull radiographs and   primary sinusitis, temporo-mandibular joint   modulate perception of afferent nociceptive
        Computed Tomography (CT).           arthritis,  nuchal  bursitis,  musculoskeletal   stimuli  by  inhibiting  afferent  pain  signals
                                            pathologies, basisphenoid fracture, otitis   and by activation of descending inhibitory
         Transverse (A) image of the head of a horse
         with marked enlargement of the left infraorbital   externa  and  a  mass  affecting  the  infra-  pathways. Electroacupuncture is believed to
         nerve (white arrows) that is causing expansion   orbital nerve.        be less invasive than PENs and may yield
         and thickening of the infraorbital canal wall                          similar results.
                                            Treatment                            Finally, surgical  treatment includes
                                            While several treatments are available,   bilateral infraorbital neurectomy, which has
                                            success rates are extremely variable. There   been  associated  with  serious  side  effects,
                                            is  also  considerable  placebo  effect  when   and caudal ablation of the infraorbital nerve
                                            interpreting results of treatments and many   via coil compression.  This procedure has
                                            unpublished treatments used by owners.   been shown to yield 50% success rate in 57
                                              Among treatment used, nose nets are   horses, with 26% relapsing within a median
                                            found  to  be  cheap,  non-invasive,  risk-free   time of nine months. Most horses developed
                                            and allowed in most competition at most   side  effects  of  nose  rubbing,  which  was
                                            levels. They are reported to give up to 70%   deemed short-term in most cases, but in
                                            relief in 25% cases and are believed to act   four of 58 cases, horses were euthanised
                                            through the gate control theory.    due  to  severity  or  nonresolution  of  these
                                              The drug gabapentin is used in    side effects.
                                            equine headshaking but it has poor
                                            bioavailability and only anecdotal reports
                                            of  success.  Carbamazepine,  which
                                            reduces central nerve conduction, is also     For equine referrals, please call: 01707
                                                                                     666297
                                                                                       Email:
                                                                                     equinehospital@rvc.ac.uk

        10   Spring 2024
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