Published: 16 Mar 2016 | Last Updated: 16 Mar 2016 14:27:42

Dr David Bishop-Bailey has been awarded a MRC grant to work on "Roles of epoxy-oxylipins in the human acute inflammatory response"

The project involves a collaboration between Dr Bishop-Bailey, Dr Caroline Hyde (Bio-analytical Lab; LBIC) and Prof Derek Gilroy (UCL).

They and others have found evidence for the presence of a new class of anti-inflammatory lipid mediators that the body itself produces called epoxy-oxylipins. So far the ability of these new mediators to act to reduce inflammation in humans is not known. With Dr Caroline Hyde the aim is to establish new cutting edge analytical techniques to measure these mediators in human and veterinary patients. With Prof Gilroy, they will measure the production of these mediators both in human inflammatory cells obtained from donor blood and in novel experimental models of inflammation in human volunteers, with the ultimate aim to test the anti-inflammatory properties of these new mediators, and drugs that can elevate them in the body.